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Articles (142)
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Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells

Siliciano, Janet D, Kajdas, Joleen, Finzi, Diana, Quinn, Thomas C, Chadwick, Karen, Margolick, Joseph B, Kovacs, Colin, Gange, Stephen J, Siliciano, Robert F

Journal:

Nature Medicine

Année:

2003

Langue:

english

Fichier:

PDF, 121 KB

english, 2003

Viral Dynamics in HIV-1 Infection

Diana Finzi, Robert F Siliciano

Journal:

Cell

Année:

1998

Langue:

english

Fichier:

PDF, 430 KB

english, 1998

Replication-Competent Noninduced Proviruses in the Latent Reservoir Increase Barrier to HIV-1 Cure

Ho, Ya-Chi, Shan, Liang, Hosmane, Nina N., Wang, Jeffrey, Laskey, Sarah B., Rosenbloom, Daniel I.S., Lai, Jun, Blankson, Joel N., Siliciano, Janet D., Siliciano, Robert F.

Journal:

Cell

Année:

2013

Langue:

english

Fichier:

PDF, 1.09 MB

english, 2013

Towards an HIV-1 cure: measuring the latent reservoir

Bruner, Katherine M., Hosmane, Nina N., Siliciano, Robert F.

Journal:

Trends in Microbiology

Année:

2015

Langue:

english

Fichier:

PDF, 544 KB

english, 2015

HIV reservoirs: what, where and how to target them

Churchill, Melissa J., Deeks, Steven G., Margolis, David M., Siliciano, Robert F., Swanstrom, Ronald

Journal:

Nature Reviews Microbiology

Année:

2015

Langue:

english

Fichier:

PDF, 159 KB

english, 2015

The Challenge of Viral Reservoirs in HIV-1 Infection

Blankson, Joel N., Persaud, Deborah, Siliciano, Robert F.

Journal:

Annual Review of Medicine

Année:

2002

Langue:

english

Fichier:

PDF, 489 KB

english, 2002

A primary CD4+ T cell model of HIV-1 latency established after activation through the T cell receptor and subsequent return to quiescence

Kim, Michelle, Hosmane, Nina N, Bullen, C Korin, Capoferri, Adam, Yang, Hung-Chih, Siliciano, Janet D, Siliciano, Robert F

Journal:

Nature Protocols

Année:

2014

Langue:

english

Fichier:

PDF, 1.43 MB

english, 2014

Genome editing for clinical HIV isolates

Kim, Michelle, Siliciano, Robert F

Journal:

Nature Biotechnology

Année:

2016

Langue:

english

Fichier:

PDF, 372 KB

english, 2016

A-101 Defective proviruses rapidly accumulate during acute HIV-1 infection

Siliciano, Robert

Journal:

JAIDS Journal of Acquired Immune Deficiency Syndromes

Année:

2017

Langue:

english

Fichier:

PDF, 2.69 MB

english, 2017

Re-evaluating evolution in the HIV reservoir

Rosenbloom, Daniel I. S., Hill, Alison L., Laskey, Sarah B., Siliciano, Robert F.

Journal:

Nature

Année:

2017

Langue:

english

Fichier:

PDF, 531 KB

english, 2017

Insight into treatment of HIV infection from viral dynamics models

Hill, Alison L., Rosenbloom, Daniel I. S., Nowak, Martin A., Siliciano, Robert F.

Journal:

Immunological Reviews

Année:

2018

Langue:

english

Fichier:

PDF, 1.13 MB

english, 2018

Different human resting memory CD4 + T cell subsets show similar low inducibility of latent HIV-1 proviruses

Kwon, Kyungyoon J., Timmons, Andrew E., Sengupta, Srona, Simonetti, Francesco R., Zhang, Hao, Hoh, Rebecca, Deeks, Steven G., Siliciano, Janet D., Siliciano, Robert F.

Journal:

Science Translational Medicine

Année:

2020

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2020

Mechanisms of HIV-1 escape from immune responses and antiretroviral drugs

Justin Bailey, Joel N Blankson, Megan Wind-Rotolo, Robert F Siliciano

Journal:

Current Opinion in Immunology

Année:

2004

Langue:

english

Fichier:

PDF, 175 KB

english, 2004

Low-level HIV-1 replication and the dynamics of the resting CD4+T cell reservoir for HIV-1 in the setting of HAART

Ahmad R Sedaghat, Robert F Siliciano, Claus O Wilke

Journal:

BMC Infectious Diseases

Année:

2008

Langue:

english

Fichier:

PDF, 822 KB

english, 2008

Viral suppression of multiple escape mutants by de novo CD8+T cell responses in a human immunodeficiency virus-1 Infected elite suppressor

Karen A O’Connell, Robert W Hegarty, Robert F Siliciano, Joel N Blankson

Journal:

Retrovirology

Année:

2011

Langue:

english

Fichier:

PDF, 381 KB

english, 2011

Reservoirs for HIV-1

Robert F. Siliciano

Journal:

Current Infectious Disease Reports

Année:

1999

Langue:

english

Fichier:

PDF, 356 KB

english, 1999

Elite Suppression of HIV-1 Replication

Joel N. Blankson, Robert F. Siliciano

Journal:

Immunity

Année:

2008

Langue:

english

Fichier:

PDF, 167 KB

english, 2008

SIV-specific T lymphocyte responses in PBMC and lymphoid tissues of SIV-infected pigtailed macaques during suppressive combination antiretroviral therapy

Lucy M. Carruth, M. Christine Zink, Patrick M. Tarwater, Michael D. Miller, Ming Li, Laurie A. Queen, Joseph L. Mankowski, Anding Shen, Robert F. Siliciano, Janice E. Clements

Journal:

Journal of Medical Primatology

Année:

2005

Langue:

english

Fichier:

PDF, 227 KB

english, 2005

Activation of cytolytic T lymphocyte and natural killer cell function through the T11 sheep erythrocyte binding protein

Siliciano, Robert F., Pratt, Joanne C., Schmidt, Reinhold E., Ritz, Jerome, Reinherz, Ellis L.

Journal:

Nature

Année:

1985

Fichier:

PDF, 354 KB

1985

A soluble CD4 protein selectively inhibits HIV replication and syncytium formation

Hussey, Rebecca E., Richardson, Neil E., Kowalski, Mark, Brown, Nicholas R., Chang, Hsiu-Ching, Siliciano, Robert F., Dorfman, Tatyana, Walker, Bruce, Sodroski, Joseph, Reinherz, Ellis L.

Journal:

Nature

Année:

1988

Fichier:

PDF, 556 KB

Chun, Tae-Wook, Finzi, Diana, Margolick, Joseph, Chadwick, Karen, Schwartz, David, Siliciano, Robert F.

Journal:

Nature Medicine

Année:

1995

Fichier:

PDF, 976 KB

1995

Experimental approaches to the study of HIV-1 latency

Han, Yefei, Wind-Rotolo, Megan, Yang, Hung-Chih, Siliciano, Janet D., Siliciano, Robert F.

Journal:

Nature Reviews Microbiology

Année:

2007

Langue:

english

Fichier:

PDF, 876 KB

english, 2007

Establishment of Latent HIV-1 Infection of Resting CD4+ T Lymphocytes Does Not Require Inactivation of Vpr

Anding Shen, Janet D. Siliciano, Theodore C. Pierson, Christopher B. Buck, Robert F. Siliciano

Journal:

Virology

Année:

2000

Langue:

english

Fichier:

PDF, 221 KB

english, 2000

DNA prime Listeria boost induces a cellular immune response to SIV antigens in the rhesus macaque model that is capable of limited suppression of SIV239 viral replication

Jean D. Boyer, Tara M. Robinson, Paulo C. Maciag, Xiaohui Peng, Ross S. Johnson, George Pavlakis, Mark G. Lewis, Anding Shen, Robert Siliciano, Charles R. Brown, David B. Weiner, Yvonne Paterson

Journal:

Virology

Année:

2005

Langue:

english

Fichier:

PDF, 827 KB

english, 2005

Prolonged control of replication-competent dual- tropic human immunodeficiency virus-1 following cessation of highly active antiretroviral therapy

Maria Salgado, S Alireza Rabi, Karen A O’Connell, Robert W Buckheit III, Justin R Bailey, Amina A Chaudhry, Autumn R Breaud, Mark A Marzinke, William Clarke, Joseph B Margolick, Robert F Siliciano, Jo

Journal:

Retrovirology

Année:

2011

Langue:

english

Fichier:

PDF, 398 KB

english, 2011

The HumanNTTGene: Identification of a Novel 17-kb Noncoding Nuclear RNA Expressed in Activated CD4+T Cells

Alice Y. Liu, Beth S. Torchia, Barbara R. Migeon, Robert F. Siliciano

Journal:

Genomics

Année:

1997

Langue:

english

Fichier:

PDF, 3.04 MB

english, 1997

Chloramphenicol metabolism in isolated rat hepatocytes

Robert F. Siliciano, Simeon Margolis, Paul S. Lietman

Journal:

Biochemical Pharmacology

Année:

1978

Langue:

english

Fichier:

PDF, 289 KB

english, 1978

Outwitting Evolution: Fighting Drug-Resistant TB, Malaria, and HIV

Daniel E. Goldberg, Robert F. Siliciano, William R. Jacobs Jr.

Journal:

Cell

Année:

2012

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2012

Orientation-Dependent Regulation of Integrated HIV-1 Expression by Host Gene Transcriptional Readthrough

Yefei Han, Yijie B. Lin, Wenfeng An, Jie Xu, Hung-Chih Yang, Karen O'Connell, Dominic Dordai, Jef D. Boeke, Janet D. Siliciano, Robert F. Siliciano

Journal:

Cell Host & Microbe

Année:

2008

Langue:

english

Fichier:

PDF, 1.22 MB

english, 2008

Stimulation of HIV-1-Specific Cytolytic T Lymphocytes Facilitates Elimination of Latent Viral Reservoir after Virus Reactivation

Liang Shan, Kai Deng, Neeta S. Shroff, Christine M. Durand, S. Alireza. Rabi, Hung-Chih Yang, Hao Zhang, Joseph B. Margolick, Joel N. Blankson, Robert F. Siliciano

Journal:

Immunity

Année:

2012

Langue:

english

Fichier:

PDF, 1.62 MB

english, 2012

The multifactorial nature of HIV-1 latency

Kara Lassen, Yefei Han, Yan Zhou, Janet Siliciano, Robert F. Siliciano

Journal:

Trends in Molecular Medicine

Année:

2004

Langue:

english

Fichier:

PDF, 435 KB

english, 2004

HIV-1-induced depletion of CD4+ T cells in the gut: mechanism and therapeutic implications

Amanda Chase, Yan Zhou, Robert F. Siliciano

Journal:

Trends in Pharmacological Sciences

Année:

2006

Langue:

english

Fichier:

PDF, 179 KB

english, 2006

A novel method for determining the inhibitory potential of anti-HIV drugs

Lin Shen, S. Alireza Rabi, Robert F. Siliciano

Journal:

Trends in Pharmacological Sciences

Année:

2009

Langue:

english

Fichier:

PDF, 384 KB

english, 2009

HIV-1 suppression by early treatment with hydroxyurea, didanosine, and a protease inhibitor

Julianna Lisziewicz, Heiko Jessen, Diana Finzi, Robert F Siliciano, Franco Lori

Journal:

The Lancet

Année:

1998

Langue:

english

Fichier:

PDF, 371 KB

english, 1998

Measurement of antiviral activity in drugs for HIV-1

Robert F Siliciano

Journal:

The Lancet Infectious Diseases

Année:

2011

Langue:

english

Fichier:

PDF, 79 KB

english, 2011

Redefining the Viral Reservoirs that Prevent HIV-1 Eradication

Eisele, Evelyn, Siliciano, Robert F.

Journal:

Immunity

Année:

2012

Langue:

english

Fichier:

PDF, 730 KB

english, 2012

Acidic residues in the DRβ chain third hypervariable region are required for stimulation of a DR(α,β1∗0402)-restricted T-cell clone

Richard R Olson, Jeffrey J Reuter, Janet McNicholl, Carol Alber, Ellen Klohe, Kevin Callahan, Robert F Siliciano, Robert W Karr

Journal:

Human Immunology

Année:

1994

Langue:

english

Fichier:

PDF, 639 KB

english, 1994

Developing strategies for HIV-1 eradication

Christine M. Durand, Joel N. Blankson, Robert F. Siliciano

Journal:

Trends in Immunology

Année:

2012

Langue:

english

Fichier:

PDF, 437 KB

english, 2012

Viral reservoirs, residual viremia, and the potential of highly active antiretroviral therapy to eradicate HIV infection

Shen, Lin, Siliciano, Robert F.

Journal:

Journal of Allergy and Clinical Immunology

Année:

2008

Langue:

english

Fichier:

PDF, 652 KB

english, 2008

Evolution of the HIV-1nefgene in HLA-B*57 Positive Elite Suppressors

Maria Salgado, Timothy P Brennan, Karen A O'Connell, Justin R Bailey, Stuart C Ray, Robert F Siliciano, Joel N Blankson

Journal:

Retrovirology

Année:

2010

Langue:

english

Fichier:

PDF, 1.33 MB

english, 2010

Host factors dictate control of viral replication in two HIV-1 controller/chronic progressor transmission pairs

Buckheit, Robert W., Allen, Tracy G., Alme, Angela, Salgado, Maria, O'Connell, Karen A., Huculak, Sarah, Falade-Nwulia, Oluwaseun, Williams, Thomas M., Gallant, Joel E., Siliciano, Robert F., Blankson

Journal:

Nature Communications

Année:

2012

Langue:

english

Fichier:

PDF, 729 KB

english, 2012

Targeting HIV latency: pharmacologic strategies toward eradication

Xing, Sifei, Siliciano, Robert F.

Journal:

Drug Discovery Today

Année:

2013

Langue:

english

Fichier:

PDF, 502 KB

english, 2013

Reservoirs for HIV-1: Mechanisms for Viral Persistence in the Presence of Antiviral Immune Responses and Antiretroviral Therapy

Pierson, Theodore, McArthur, Justin, Siliciano, Robert F.

Journal:

Annual Review of Immunology

Année:

2000

Langue:

english

Fichier:

PDF, 293 KB

english, 2000

Primary CD8+T cells from elite suppressors effectively eliminate non-productively HIV-1 infected resting and activated CD4+T cells

Robert W Buckheit III, Robert F Siliciano, Joel N Blankson

Journal:

Retrovirology

Année:

2013

Langue:

english

Fichier:

PDF, 477 KB

english, 2013